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| Purvis JE, Karhohs KW, Mock C,
Batchelor E, Loewer A, Lahav G. p53 dynamics control cell fate.
In revision |
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| Chatterjee MS, Purvis JE, Brass LF,
Diamond SL. Pairwise agonist scanning predicts cellular
signaling responses to combinatorial stimuli.
(2010) Nature Biotechnology 28(7):727-32. |
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| Shah PP, Wang T, Kaletsky RL, Myers
MC, Purvis JE, Jing H, Huryn DM, Greenbaum DC, Smith AB 3rd,
Bates P, Diamond SL. A small-molecule oxocarbazate inhibitor of
human cathepsin L blocks severe acute respiratory syndrome and
ebola pseudotype virus infection into human embryonic kidney
293T cells.
(2010) Molecular Pharmacology 78(2):319-24. |
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| Purvis JE, Radhakrishnan R, Diamond
SL. Steady-state kinetic modeling constrains cellular resting states and dynamic behavior.
(2009) PLoS Computational Biology 5(3):e1000298. |
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| Beavers MP, Myers MC, Shah PP,
Purvis JE, Diamond SL, Cooperman BS, Huryn DM, Smith AB 3rd.
Molecular docking of cathepsin L inhibitors in the binding site
of papain. (2008) Journal of Chemical Information and Modeling 48(7):1464-72. |
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| Purvis JE, Chatterjee MS, Brass LF,
Diamond SL. A molecular signaling model of platelet phosphoinositide and
calcium regulation during homeostasis and P2Y1 activation. (2008)
Blood 112(10):4069-79. |
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| Purvis, J, Ilango, V, Radhakrishnan,
R. Role of Network Branching in Eliciting Differential Short-Term
Signaling Responses in the Hyper-Sensitive Epidermal Growth
Factor Receptor Mutants Implicated in Lung Cancer. (2008) Biotechnology
Progress 24(3):540-53. |
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| Shah PP, Myers MC, Beavers MP, Purvis
JE, Jing H, Grieser HJ, Sharlow ER, Napper AD, Huryn DM, Cooperman
BS, Smith AB, Diamond SL. Kinetic Characterization and Molecular
Docking of a Novel, Potent, and Selective Slow-binding Inhibitor
of Human Cathepsin L. (2008) Molecular Pharmacology 74(1):34-41. |
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| Purvis J, Liu Y, Ilango V, Radhakrishnan
R. Efficacy of tyrosine kinase inhibitors in the mutants of
the epidermal growth factor receptor through a multiscale molecular/
systems model for phosphorylation and inhibition. (2007) Proceedings
of Foundations of Systems Biology in Engineering. |
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| Liu Y, Purvis J, Shih A, Weinstein
J, Agrawal N, Radhakrishnan R. A multiscale computational approach
to dissect early events in the Erb family receptor mediated
activation, differential signaling, and relevance to oncogenic
transformations. (2007) Annals of Biomedical Engineering 35(6):1012-25. |
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| Purvis JE, Yomano LP, Ingram LO.
Enhanced trehalose production improves growth of Escherichia
coli under osmotic stress. Applied and Environmental Microbiology (2005)
71:3761-9. |
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| Gonzalez R, Tao H, Purvis JE, York
SW, Shanmugam KT, Ingram LO. Gene array-based identification
of changes that contribute to ethanol tolerance in ethanologenic
Escherichia coli: comparison of KO11 (parent) to LY01 (resistant
mutant). Biotechnology Progress (2003) 19:612-23. |
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