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Jeremy is the sole member
of the Purvis Lab. Born in Sarasota, Florida in 1979, he received
a B.S. (2002) and M.S. (2004) in Microbiology from the University
of Florida under the supervision of Lonnie
Ingram. In a bold display of adventure, Jeremy left the
golden shores of Florida to pursue a degree in Genomics
and Computational Biology at the University
of Pennsylvania in Philadelphia. Mentored by Scott Diamond
(Chemical Engineering) and Ravi Radhakrishnan (Bioengineering),
his doctoral work has focused on understanding cellular signaling
from a systems perspective. |
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Here are a few unpublished writing
samples: |
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On the
Emerging Complexity of Gene Expression |
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This piece was written for the Literature Review and
Analysis portion of the 2007 Genomics and Computational
Biology preliminary exam 2007. Penn has an especially high
concentration of genome-wide association expertise and the
focus of this analysis was the variability in gene expression
— itself a heritable trait
detectable by genetical genomics. |
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A Critical Assessment of the
Bayesian Approach to Causal Network Inference |
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Written as
a assignment for an independent study (Statistical
Methods in Bioinformatics), this piece was intended
mostly to humor our illustrious statistician and friend,
Warren Ewens.
A student of the frequentist old school, Warren was somewhat
suspicious of Bayesian analysis and once interrupted class to
ask each student to confess whether they were a Bayesian or a
Frequentist (he compared this distinction to being either
protestant or catholic, with shades in between).
Despite the biting tone of the critique, I am actually a big
fan of the
Sachs
article as it has greatly influenced my thinking. |
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Generalizability of Machine
Learning Methods in Bioinformatics |
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Also a class
assignment (Principles
in Computational Biology), this paper examines a
recent collection of machine learning techniques and focuses on the generalizability of each method. |
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Combined Statistical Methods
for Describing Interacting Protein Networks |
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A
back-of-the-envelope method for generating probabilistic
models of protein-protein interaction networks with spatial
resolution. Not my most stellar effort; probably won't get
funded. |
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A Systems
Approach to Cellular Signal Transduction |
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My Ph.D. thesis. If you happen to be taking a 14-hour flight,
feel free to read this one. |
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Guest Blog Posts |
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I have had the great honor of contributing guest posts to
Becky Ward's infamous
ittakes30 blog,
the highly venerated mouthpiece of systems biology. Here's one
on
Ontogeny and Phylogeny and a review of the 2010
Koch Institute Summer Symposium. |
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An excellent guest post by Andrew Murray on
How to Give a Science Talk. |
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