Welcome to the Purvis Lab

In hope of one day acquiring some real laboratory space, purvislab.org serves as a makeshift home for the various projects and personalities I've encountered over the years. My research interests are loosely centered around quantitative approaches to understanding cell signaling and cell fate decisions. Lately, I've been focused on the dynamics of entry into cellular senescence—a state of permanent cell cycle arrest.

I did my graduate work with Scott Diamond and Ravi Radhakrishanan at the University of Pennsylvania. Our efforts led to insight into human platelet activation and oncogenic signaling via the epidermal growth factor receptor. Before working at Penn, I trained as a Master's student under Lonnie Ingram at the University of Florida learning the fundamentals of molecular biology. In September of 2009, I joined Galit Lahav's laboratory in the Department of Systems Biology at Harvard Medical School. One of our current goals is trying to understand how cells protect themselves from DNA damage.

You can read more about my research interests here.folded paper

Here is my obligatory CV.

SEE ALSO:
Lahav Lab | DNA damage and cell signaling at HMS
Diamond Lab | blood biology and drug discovery at UPenn
Radhakrishnan Lab | multiscale modeling lab at UPenn
Brass Lab | platelet signaling lab at UPenn
Ingram Lab | metabolic engineering lab at UF