Many important questions in biology and disease take place at the level of individual cells. A classic example is: why do some cells respond to chemotherapy, while others do not? Answering such questions requires taking measurements at single-cell resolution and, if possible, in real time. Our research combines time-lapse microscopy, single-molecule mRNA detection, and computational modeling to study signal processing events in human cells. We are focused specifically on understanding mechanisms of cellular senescence—a state of permanent cell cycle arrest that is strongly implicated in tumor suppression and aging.

You can read a more detailed description of our research interests here.

These are the wonderful labs where I've spent time:
Lahav Lab | DNA damage and cell signaling at HMS
Diamond Lab | blood biology and drug discovery at UPenn
Radhakrishnan Lab | multiscale modeling lab at UPenn
Brass Lab | platelet signaling lab at UPenn
Ingram Lab | metabolic engineering lab at UF